1. noun
    the outermost or farthest region or point
  2. noun
    an external body part that projects from the body; "it is important to keep the extremities warm"
  3. noun
    that part of a limb that is farthest from the torso
  4. noun
    the greatest or utmost degree; "the extremity of despair"
  5. noun
    an extreme condition or state (especially of adversity or disease)